Alkylating Agents

Ifex (ifosfamide)

Ifosfamide (IFO), sold under the brand name Ifex among others, is a chemotherapy medication used to treat a number of types of cancer. This includes testicular cancer, soft tissue sarcoma, osteosarcoma, bladder cancer, small cell lung cancer, cervical cancer, and ovarian cancer... Wikipedia

 

 

Manufacturer's Website: None  Available                                                                                                                     Average retail cost: *

 

 

*This prescription is provided by your healthcare provider. It can not be filled in a pharmacy and may be expensive.

Myleran (busulfan)

Busulfan was approved by the US Food and Drug Administration (FDA) for treatment of chronic myeloid leukemia (CML) in 1999. Busulfan was the mainstay of the chemotherapeutic treatment of chronic myeloid leukemia (CML) until it was displaced by the new gold standard, imatinib, though it is still in use to a degree as a result of the drug's relative low cost...Wikipedia

 

 

Manufacturer's Website: None  Available                                                                                                                     Average retail cost: $347/month

Cytoxan (cyclophosphamide)

Cyclophosphamide (CP), also known as cytophosphane among other, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma...Wikipedia

 

 

Manufacturer's Website: None  Available                                                                                                                     Average retail cost: *

 

 

* The drug is no longer available as it has been discontinued by the manufacturer.

Treanda (bendamustine)

Bendamustine, sold under the brand name Treanda among others, is a chemotherapy medication used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma. It is given by injection into a vein...Wikipedia

 

 

Manufacturer's Website: None  Available                                                                                                                     Average retail cost: *

 

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Paraplatin (carboplatin)

Carboplatin is a chemotherapy medication used to treat a number of forms of cancer. This includes ovarian cancer, lung cancer, head and neck cancer, brain cancer, and neuroblastoma. It is used by injection into a vein...Wikipedia

 

* Paraplatin has been discontinued by the manufacturer and is now only available as the generic carboplatin.

 

Manufacturer's Website: None  Available                                                                                                                     Average retail cost: *

 

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Leukeran (chlorambucil)

Chlorambucil, sold under the brand name Leukeran among others, is a chemotherapy medication used to treat chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, and non-Hodgkin lymphoma. For CLL it is a preferred treatment. It is given by mouth...Wikipedia

 

 

Manufacturer's Website: None  Available                                                                                                                     Average retail cost: *$750/month

Neosar (cyclophosphamide)

Cyclophosphamide (CP), also known as cytophosphane among other, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. As an immune suppressor it is used in nephrotic syndrome and following organ transplant. It is taken by mouth or injection into a vein...Wikipedia

 

* Neosar has been discontinued by the manufacturer and is now only available as the generic cyclophosphamide.

 

Manufacturer's Website: None  Available                                                                                                                 Average retail cost: $750/month/tabs--*inj.

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Platinol (cisplatin)

Cisplatin is a chemotherapy medication used to treat a number of cancers. This includes testicular cancer, ovarian cancer, cervical cancer, breast cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is used by injection into a vein...Wikipedia

 

* Platinal has been discontinued by the manufacturer and is now only available as the generic cisplatin.

 

Manufacturer's Website: None  Available                                                                                                                     Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Temodar (temozolomide)

Temozolomide (TMZ; brand names Temodar and Temodal and Temcad) is an oral chemotherapy drug. It is an alkylating agent used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme...Wikipedia

 

* Platinal has been discontinued by the manufacturer and is now only available as the generic cisplatin.

 

Manufacturer's Website: None  Available                                                                                                              Average retail cost: $2,600/month/tabs-- *inj.

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Alkeran (melphalan)

Melphalan (trade name Alkeran, in former USSR also known as Sarcolysin) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents. It is used to treat multiple myeloma, ovarian cancer, AL amyloidosis, and occasionally malignant melanoma....Wikipedia

 

Manufacturer's Website: None  Available                                                                                                              Average retail cost: $366/month/tabs-- *inj.

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Busulfex (busulfan)

Busulfan (Myleran, GlaxoSmithKline, Busulfex IV, Otsuka America Pharmaceutical, Inc.) is a cancer drug, in use since 1959. Busulfan was approved by the US Food and Drug Administration (FDA) for treatment of chronic myeloid leukemia (CML) in 1999. Busulfan was the mainstay of the chemotherapeutic treatment of chronic myeloid leukemia (CML) until it was displaced by the new gold standard, imatinib, though it is still in use to a degree as a result of the drug's relative low cost...Wikipedia

 

 

Manufacturer's Website: None  Available                                                                                                              Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Bendeka (bendamustine)

Bendeka is a chemotherapy drug. It is used to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma.

 

 

Manufacturer's Website: Bendeka                                                                                                             Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

BiCNU (carmustine)

Carmustine (bis-chloroethylnitrosourea, BCNU, BiCNU) is a medication used mainly for chemotherapy and sometimes for immunosuppression before organ transplantation. It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent...Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                             Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

CCNSB (lomustine)

Lomustine (INN), abbreviated CCNU (original brand name (formerly available) is CeeNU, now marketed as Gleostine), is an alkylating nitrosourea compound used in chemotherapy. It is closely related to semustine and is in the same family as streptozotocin. It is a highly lipid-soluble drug, thus it crosses the blood-brain barrier. This property makes it ideal for treating brain tumors, which is its primary use. Lomustine has a long time to nadir (the time when white blood cells reach their lowest number). Unlike carmustine, lomustine is administered orally ... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                             Average retail cost: *

 

* The drug is no longer available as it has been discontinued by the manufacturer.

CeeNU (lomustine)

Lomustine (INN), abbreviated CCNU (original brand name (formerly available) is CeeNU, now marketed as Gleostine), is an alkylating nitrosourea compound used in chemotherapy. It is closely related to semustine and is in the same family as streptozotocin. It is a highly lipid-soluble drug, thus it crosses the blood-brain barrier. This property makes it ideal for treating brain tumors, which is its primary use. Lomustine has a long time to nadir (the time when white blood cells reach their lowest number). Unlike carmustine, lomustine is administered orally ... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                             Average retail cost: *

 

* The drug is no longer available as it has been discontinued by the manufacturer.

Cytoxan Lyophilized (cyclophosphamide)

Cyclophosphamide (CP), also known as cytophosphane among other, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. As an immune suppressor it is used in nephrotic syndrome and following organ transplant. It is taken by mouth or injection into a vein... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                             Average retail cost: *

 

* The drug is no longer available as it has been discontinued by the manufacturer.

DTIC-Dome (dacarbazine)

Dacarbazine (DTIC), also known as imidazole carboxamide, is a chemotherapy medication used in the treatment of melanoma and Hodgkin's lymphoma. For Hodgkin's it is often used together with vinblastine, bleomycin, and doxorubicin. It is given by injection into a vein... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                             Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Eloxatin (oxaliplatin)

Oxaliplatin, sold under the brand name Eloxatin, is a cancer medication used to treat colorectal cancer. Often it is used together with fluorouracil and folinic acid (leucovorin) in advanced cancer. It is given by injection into a vein... Wikipedia

 

Manufacturer's Website: Eloxatin                                                                                                                                                                 Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Evomela (melphalan)

Melphalan (trade name Alkeran, in former USSR also known as Sarcolysin) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents. It is used to treat multiple myeloma, ovarian cancer, AL amyloidosis, and occasionally malignant melanoma...Wikipedia

 

Manufacturer's Website: Evomela                                                                                                                                                               Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Gleostine (lomustine)

Lomustine (INN), abbreviated CCNU (original brand name (formerly available) is CeeNU, now marketed as Gleostine), is an alkylating nitrosourea compound used in chemotherapy. It is closely related to semustine and is in the same family as streptozotocin. It is a highly lipid-soluble drug, thus it crosses the blood-brain barrier. This property makes it ideal for treating brain tumors, which is its primary use...Wikipedia

 

 

Manufacturer's Website: Evomela                                                                                                                                                Average retail cost: $534/dose

Gliadel (carmustine)

In the treatment of brain tumours, the U.S. Food and Drug Administration (FDA) approved biodegradable discs infused with carmustine (Gliadel). They are implanted under the skull during a surgery called a craniotomy. The disc allows for controlled release of carmustine in the extracellular fluid of the brain, thus eliminating the need for the encapsulated drug to cross the blood-brain barrier...Wikipedia

 

 

Manufacturer's Website: Gliadel                                                                                                                                             Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Mustargen (mechlorethamine)

In the treatment of brain tumours, the U.S. Food and Drug Administration (FDA) approved biodegradable discs infused with carmustine (Gliadel). They are implanted under the skull during a surgery called a craniotomy. The disc allows for controlled release of carmustine in the extracellular fluid of the brain, thus eliminating the need for the encapsulated drug to cross the blood-brain barrier. It has been derivatized into the estrogen analogue estramustine phosphate, used to treat prostate cancer...Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                                            Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Platinol-AQ (cisplatin)

Cisplatin is a chemotherapy medication used to treat a number of cancers. This includes testicular cancer, ovarian cancer, cervical cancer, breast cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is used by injection into a vein...Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                                            Average retail cost: *

 

* The drug is no longer available as it has been discontinued by the manufacturer.

Tepadina (thiotepa)

Thiotepa (INN, chemical name: N,N′,N′′-triethylenethiophosphoramide) is an alkylating agent used to treat cancer.  Thiotepa is indicated for use in combination with other chemotherapeutic agents. This can be with or without total body irradiation (TBI), as a conditioning treatment prior to allogeneic or autologous hematopoietic progenitor cell transplantation (HPCT) in hematological diseases in adult and pediatric patients. These diseases include Hodgkin's disease and leukaemia. Thiotepa is also used with high-dose chemotherapy with HPCT support to treat certain solid tumors in adult and pediatric patient..Wikipedia

 

 

Manufacturer's Website: Tepadina                                                                                                                                         Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Thioplex (thiotepa)

Thiotepa is for superficial papillary carcinoma of the urinary bladder. Intracavitary effusion due to neoplasm of serosal cavities.

 

 

Manufacturer's Website: Not Available                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Yondelis (trabectedin)

Trabectedin (also known as ecteinascidin 743 or ET-743) is an anti-tumor chemotherapy drug. It is sold by Pharma Mar S.A. and Johnson and Johnson under the brand name Yondelis. It is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma. It is also undergoing clinical trials for the treatment of breast, prostate, and paediatric sarcomas. The European Commission and the U.S. Food and Drug Administration (FDA) have granted orphan drug status to trabectedin for soft tissue sarcomas and ovarian cancer ... Wikipedia

 

Manufacturer's Website: Yondelis                                                                                                                                     Average retail cost: $2,739/vial

 

Zanosar (streptozocin)

Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the islets of Langerhans and used in medical research to produce an animal model for hyperglycemia in a large dose, as well as type 2 diabetes or type 1 diabetes with multiple low doses... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                                    Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

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