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A20-A28 Certain Zoonotic Bacterial Diseases

A20 Plague

A21 Tularemia

A22 Anthrax

A23 Brucellosis

A24 Glanders and Melioidosis

A25 Rat-Bite Fevers

Certain zoonotic bacterial diseases A20-A28 >



infection due to Yersinia pestis

Clinical Information

A gram-negative bacterial infection caused by yersinia pestis.

It is usually transmitted to humans from bites of infected

rodent fleas. It is manifested as a bubonic, septicemic, or

pneumonic plague. In bubonic plague, the lymph nodes adjacent

to the site of the skin bite are infected and enlarged. In

septicemic plague, the infection spreads directly through the

bloodstream. In pneumonic plague, the infection spreads to the

lungs either following bubonic plague, or by inhalation of

infective droplets. If untreated, it may lead to death.

Acute infectious disease caused by yersinia pestis that affects

humans, wild rodents, and their ectoparasites; bubonic plague

is the most common form.

An acute infectious disease caused by yersinia pestis that

affects humans, wild rodents, and their ectoparasites. This

condition persists due to its firm entrenchment in sylvatic

rodent-flea ecosystems throughout the world. Bubonic plague

is the most common form.

An infectious disease

Plague is an infection caused by the bacterium yersinia pestis.

The bacteria are found mainly in rats and in the fleas that

feed on them. People and other animals can get plague from rat

or flea bites. Historically, plague destroyed entire civilizations.

In the 1300s, the "black death," as it was called, killed approximately

one-third of europe's population. Today plague is uncommon. This is

largely due to better living conditions and antibiotics. There are

three forms of plague:

bubonic, which causes the tonsils, adenoids, spleen and thymus to

become inflamed. Symptoms include fever, aches, chills and tender

lymph glands

septicemic, in which bacteria multiply in the blood. It causes fever,

chills, shock and bleeding under the skin or other organs

pneumonic, in which the bacteria enter the lungs and cause pneumonia.

People with the infection can spread this form to others. This type

could be a bioterror agent

treatment for plague is a strong antibiotic.

There is no vaccine for plague.


Tularemia A21- >


deer-fly fever

infection due to Francisella tularensis

rabbit fever

Clinical Information

A plague-like disease of rodents, transmissible to man. It is

caused by francisella tularensis and is characterized by fever,

chills, headache, backache, and weakness.

A serious gram-negative bacterial infection caused by francisella

tularensis. It is transmitted to humans through bites from infected

insects, inhaling airborne bacteria, handling infected animals, or

consuming contaminated food or water. Signs and symptoms include

skin ulcers, mouth sores, lymphadenopathy, sore throat, fever and


Disease caused by francisella tularensis and transmitted to man

from rodents through the bite of a deer fly, chrysops discalis,

and other bloodsucking insects; symptoms consist of a prolonged

fever and often swelling of the lymph nodes; rabbits are important

reservoir hosts.


Anthrax A22- >



infection due to Bacillus anthracis

Clinical Information

An acute infection caused by the spore-forming bacteria bacillus

anthracis. It commonly affects hoofed animals such as sheep and

goats. Infection in humans often involves the skin (cutaneous

anthrax), the lungs (inhalation anthrax), or the gastrointestinal

tract. Anthrax is not contagious and can be treated with antibiotics.

An infection caused by bacillus anthracis bacteria. It may affect

the lungs, gastrointestinal tract, or skin. Patients with lung

infection present with fever, headaches, cough, chest pain and

shortness of breath. Patients with gastrointestinal infection

present with nausea, vomiting and bloody diarrhea. Patients with

skin infection develop blisters and ulcers.

Anthrax is a disease caused by bacillus anthracis, a microbe that

lives in soil. Many people know about it from the 2001 bioterror

attacks. In the attacks, someone purposely spread anthrax through

the United States Mail. This killed five people and made 22 sick.

Anthrax affects farm animals more often than people. But it can

cause three forms of disease in people. They are:

cutaneous, which affects the skin. People with cuts or open sores

can get it if they touch the bacteria.

inhalation, which affects the lungs. You can get this if you

breathe in spores of the bacteria.

gastrointestinal, which affects the digestive system. You can

get it by eating infected meat.

antibiotics often cure anthrax if it is diagnosed early. But

many people don't know they have anthrax until it is too late

to treat. A vaccine to prevent anthrax is available for people

in the military and others at high risk.

Infectious bacterial zoonotic disease usually acquired by

ingestion of bacillus anthracis; marked by hemorrhage and

serous effusions in the organs and cavities and symptoms of

extreme prostration.


Brucellosis A23- >



Malta fever

Mediterranean fever

undulant fever

Clinical Information

A gram negative bacterial infection caused by bacteria of the

genus brucella. Humans are infected by ingesting unpasteurized

milk or meat from infected animals. Signs and symptoms include

fevers, sweating, weakness, headache, muscle pain, arthritis

and anemia.

Infection caused by bacteria of the genus brucella mainly

involving the mononuclear phagocyte system. This condition

is characterized by fever, weakness, malaise, and weight loss.


Rat-bite fevers A25- >


Clinical Information

A syndrome characterized by recurring fever, rash, and

arthralgias occurring days to weeks after a rat bite. The

causative agents are either streptobacillus moniliformis

or spirillum minus.


Erysipeloid A26- >


Clinical Information

An infection caused by erysipelothrix rhusiopathiae that

is almost wholly restricted to persons who in their occupation

handle infected fish, shellfish, poultry, or meat. Three forms

of this condition exist: a mild localized form manifested by

local swelling and redness of the skin; a diffuse form that

might present with fever; and a rare systemic form associated

with endocarditis.


Leptospirosis A27- >


Clinical Information

A contagious bacterial infection caused by spirochetes of the

genus leptospira. Humans are infected by contact with water and

soil which have been contaminated with animal waste products.

The signs and symptoms include an initial flu-like phase, followed

by a second phase in which patients may develop meningitis, liver

failure and renal failure.

Infections with bacteria of the genus leptospira.


A27 Leptospirosis

A28 Other Zoonotic Bacterial Diseases-Not Elsewhere Classified

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