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Miscellaneous Antineoplastics

Vidaza (azacitidine)

Azacitidine (INN; trade name Vidaza) is a chemical analog of cytidine, a nucleoside in DNA and RNA. Azacitidine and its deoxy derivative, decitabine (also known as 5-aza-2′-deoxycytidine), are used in the treatment of myelodysplastic syndrome. Both drugs were first synthesized in Czechoslovakia as potential chemotherapeutic agents for cancer...Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                                           Average retail cost: $650/vial

Hycamtin (topotecan)

Topotecan (trade name Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor. It is a synthetic, water-soluble analog of the natural chemical compound camptothecin. It is used in the form of its hydrochloride salt to treat ovarian cancer, lung cancer and other cancer types...Wikipedia

 

 

Manufacturer's Website: Not Available                                                                                                                                           Average retail cost: $1,200/vial

Venclexta (venetoclax)

Venetoclax (INN, trade name Venclexta and Venclyxto in Europe) is a small molecule oral drug that treats chronic lymphocytic leukemia (CLL) in those with a specific chromosomal abnormality...Wikipedia

 

 

Manufacturer's Website: Venclexta                                                                                                                                          Average retail cost: $1,350/vial

Onivyde (irinotecan liposomal)

Irinotecan, sold under the brand name Camptosar among others, is a medication used to treat colon cancer and small cell lung cancer. For colon cancer it is used either alone or with fluorouracil. For small cell lung cancer it is used with cisplatin. It is given by slow injection into a vein... Wikipedia

 

 

Manufacturer's Website: Onivyde                                                                                                                                          Average retail cost: $1,830/vial

Empliciti (elotuzumab)

Elotuzumab (brand name Empliciti, previously known as HuLuc63) is a humanized monoclonal antibody used in relapsed multiple myeloma. The package insert denotes its mechanism as a SLAMF7-directed (also known as CD 319) immunostimulatory antibody... Wikipedia

 

 

Manufacturer's Website: Empliciti                                                                                                                                          Average retail cost: $1,900/vial

Proleukin (aldesleukin)

Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity... Wikipedia

 

 

Manufacturer's Website: Proleukin                                                                                                                                         Average retail cost: $2,650/vial

Thalomid (thalidomide)

Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy... Wikipedia

 

 

Manufacturer's Website: Thalomid                                                                                                                                         Average retail cost: $4,850/vial

Synribo (omacetaxine)

Omacetaxine mepesuccinate (INN, trade names Synribo or Myelostat ), formerly named as homoharringtonine or HHT, is a pharmaceutical drug substance that is indicated for treatment of chronic myeloid leukemia (CML)... Wikipedia

 

 

Manufacturer's Website: Synribo                                                                                                                                         Average retail cost: $8,000/vial

Unituxin (dinutuximab)

Dinutuximab (tradename Unituxin) is a monoclonal antibody that targets glycolipid GD2, expressed on neuroblastoma cells and on normal cells of neuroectodermal origin, including the central nervous system and peripheral nerves. It was approved for use, in combination with granulocyte-macrophage colony stimulating factor (GM-CSF), interleukin-2 (IL-2) and 13-cis-retinoic acid (RA), for high-risk neuroblastoma in pediatric patients who have at least partially responded to other first line treatments; it received FDA approval on March 10, 2015... Wikipedia

 

 

Manufacturer's Website: Synribo                                                                                                                                         Average retail cost: $9,000/vial

Zytiga (abiraterone)

Abiraterone acetate (brand names Zytiga, Abiratas, Abretone, Abirapro) is a steroidal CYP17A1 inhibitor and by extension androgen synthesis inhibitor which is used in combination with prednisone in metastatic castration-resistant prostate cancer (previously called hormone-resistant or hormone-refractory prostate cancer) – i.e., prostate cancer not responding to androgen deprivation or treatment with androgen receptor antagonists... Wikipedia

 

 

Manufacturer's Website: Zytiga                                                                                                                                       Average retail cost: $10,500/vial

Pomalyst (pomalidomide)

Pomalidomide (INN; marketed as Pomalyst in the U.S. and Imnovid in the EU and Russia) is a derivative of thalidomide marketed by Celgene. It is anti-angiogenic and also acts as an immunomodulator. Pomalidomide was approved in February 2013 by the U.S. Food and Drug Administration (FDA) as a treatment for relapsed and refractory multiple myeloma... Wikipedia

 

 

Manufacturer's Website: Pomalyst                                                                                                                                       Average retail cost: $16,500/vial

Revlimid (lenalidomide)

It was initially intended as a treatment for multiple myeloma, for which thalidomide is an accepted therapeutic treatment. Lenalidomide has also shown efficacy in the class of hematological disorders known as myelodysplastic syndromes (MDS). Along with several other drugs developed in recent years, lenalidomide has significantly improved overall survival in myeloma (which formerly carried a poor prognosis), although toxicity remains an issue for users... Wikipedia

 

 

Manufacturer's Website: Revlimid                                                                                                                                       Average retail cost: $19,000/vial

Targretin (bexarotene)

Bexarotene (brand name: Targretin) is an antineoplastic (anti-cancer) agent approved by the U.S.Food and Drug Administration (FDA) (in late 1999) and the European Medicines Agency (EMA) (early 2001) for use as a treatment for cutaneous T cell lymphoma (CTCL)... Wikipedia

 

 

Manufacturer's Website: Targretin                                                                                                                                       Average retail cost: $25,000/vial

Camptosar (irinotecan)

Irinotecan, sold under the brand name Camptosar among others, is a medication used to treat colon cancer and small cell lung cancer. For colon cancer it is used either alone or with fluorouracil. For small cell lung cancer it is used with cisplatin. It is given by slow injection into a vein... Wikipedia

 

 

Manufacturer's Website: Camptosar                                                                                                                                       Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Blincyto (blinatumomab)

Blinatumomab (trade name Blincyto, previously known as AMG103 and MT103) is a biopharmaceutical drug used as a second-line treatment for Philadelphia chromosome-negative relapsed or refractory acute lymphoblastic leukemia... Wikipedia

 

 

Manufacturer's Website: Blincyto                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Erwinaze (asparaginase erwinia chrysanthemi)

Asparaginase is an enzyme that is used as a medication and in food manufacturing. As a medication it is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin... Wikipedia

 

 

Manufacturer's Website: Erwinaze                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Ontak (denileukin diftitox)

Denileukin diftitox (trade name Ontak) was an antineoplastic agent, an engineered protein combining Interleukin-2 and Diphtheria toxin. Denileukin diftitox could bind to Interleukin-2 receptors and introduce the diphtheria toxin into cells that express those receptors, killing the cells. In some Leukemias and Lymphomas malignant cells express these receptors, so denileukin diftitox can target these.

In 1999 Ontak was approved by the U.S. Food and Drug Administration (FDA) for treatment of Cutaneous T-cell lymphoma (CTCL)... Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Imlygic (talimogene laherparepvec

Talimogene laherparepvec (T-Vec, tradenamed Imlygic, formerly called OncoVexGM-CSF) is a biopharmaceutical drug to treat melanoma lesions that cannot be operated on; it is injected directly into the lesion... Wikipedia

 

Manufacturer's Website: Imlygic                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Lartruvo (olaratumab)

Olaratumab (trade name Lartruvo) is a monoclonal antibody developed by Eli Lilly and Company for the treatment of solid tumors. It is directed against the platelet-derived growth factor receptor alpha... Wikipedia

 

Manufacturer's Website: Lartruvo                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Photofrin (porfimer)

Porfimer sodium, sold as Photofrin, is a photosensitizer used in photodynamic therapy and radiation therapy and for palliative treatment of obstructing endobronchial non-small cell lung carcinoma and obstructing esophageal cancer... Wikipedia

 

Manufacturer's Website: Photofrin                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Trisenox (arsenic trioxide)

Despite the well known toxicity of arsenic, arsenic trioxide has long been of biomedical interest, dating to traditional Chinese medicine, where it is known as pi-shuang and is still used to treat cancer and other conditions, and to homeopathy, where it is called arsenicum album. The combination therapy of arsenic trioxide and all-trans retinoic acid (ATRA) has been approved by the U.S. Food and Drug Administration (FDA) for treatment of certain leukemias ... Wikipedia

 

Manufacturer's Website: Trisenox                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

Visudyne (verteporfin)

Verteporfin (trade name Visudyne), a benzoporphyrin derivative, is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration ... Wikipedia

 

Manufacturer's Website: Visudyne                                                                                                                                      Average retail cost: *

 

* This prescription is provided by your healthcare provider. It cannot be filled in a pharmacy and may be expensive.

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